Every biomarker we measure, what it tells you about your body, and what an optimal value looks like — written in plain language by our clinical team.
The single largest cause of premature death in the developed world. We measure cardiovascular and metabolic health across 22 markers — the same markers used by preventive cardiology clinics like the Cleveland Clinic — to detect risk decades before symptoms.
A direct count of every atherogenic particle in your blood — the single best predictor of cardiovascular disease, more accurate than LDL alone. If you measure one marker for heart health, measure this one.
A largely genetic risk factor for early heart attack and stroke. One in five people carry an elevated level and most never know — it's not in the standard lipid panel. Worth measuring at least once in your life.
The "bad" cholesterol most people have heard of. Useful but incomplete on its own — ApoB tells you more about actual particle burden.
The "good" cholesterol — but higher isn't always better. We look at function, particle size, and the ratio to ApoB.
The form fat takes in your bloodstream. Highly responsive to diet, alcohol and metabolic health. Elevated triglycerides are an early warning of insulin resistance.
A sum of all cholesterol particles. Useful as a screen but not informative on its own — the breakdown matters far more.
The earliest warning of metabolic dysfunction — rises years before glucose does. If insulin is climbing, your body is working harder to keep sugar normal.
Your blood sugar after a fast. A standard marker — but elevated fasting glucose usually means insulin has been compensating for years already.
Your average blood sugar over the past three months — the gold-standard marker for tracking metabolic health over time.
A calculated index of insulin resistance, derived from fasting glucose and insulin. One of the cleanest single numbers for metabolic health.
The actual count of LDL particles — more informative than LDL-C when particle size is small and dense.
Small, dense LDL particles are more atherogenic than large, fluffy ones. Two people with the same LDL-C can have very different risk.
The cholesterol carried in very-low-density lipoproteins. Elevated levels are linked to metabolic disease.
All atherogenic cholesterol added together. A useful single number that approximates ApoB.
A simple ratio that's a strong proxy for insulin resistance. Low ratios are reassuring.
A measure of your body's insulin production. Useful for distinguishing types of glucose dysregulation.
A hormone secreted by fat cells. Higher adiponectin is linked to better insulin sensitivity and lower cardiovascular risk.
The hormone that signals satiety. Elevated leptin often indicates leptin resistance, a common feature of metabolic syndrome.
The structural protein of HDL — a more accurate measure of "good" particle quantity than HDL-C alone.
Atherogenic vs protective particles in a single number — one of the strongest single predictors of heart attack risk.
The damaged form of LDL that actually drives plaque formation. Reflects the interaction between cholesterol and inflammation.
A shorter-term measure of average glucose (2–3 weeks) — useful when HbA1c is unreliable.
Hormones are the body's messengers, regulating energy, mood, sleep, libido, recovery and metabolic rate. We measure thyroid, sex, stress and growth hormones to build a complete picture of your endocrine system.
The brain's signal to the thyroid. Sensitive to subtle thyroid dysfunction long before symptoms appear.
The thyroid hormone in circulation. Measured directly rather than via TSH for accuracy.
The active form of thyroid hormone — what your cells actually use. Often missing from standard panels.
An inactive thyroid hormone that competes with T3. Elevated rT3 can mean your body is in a stressed, conservation mode.
Autoimmune markers that detect Hashimoto's thyroiditis years before clinical disease.
A foundational hormone for muscle, libido, mood and metabolic health — in both men and women.
The biologically active fraction. Often a more meaningful number than total testosterone.
The primary form of estrogen. Important for bone, brain and cardiovascular health in both sexes.
Balances estrogen and supports sleep, mood and reproductive health.
Sex hormone binding globulin — controls how much testosterone and estrogen are biologically active.
The most abundant steroid hormone in your body. Declines with age and stress.
The primary stress hormone. Should be highest in the morning; chronic dysregulation links to almost every modern disease.
Brain signals to the gonads. Track reproductive health and detect early menopause / andropause.
Elevated prolactin can disrupt sex hormones and indicate pituitary issues.
Chronic low-grade inflammation is the root of nearly every age-related disease, from heart attack to dementia to cancer. These markers detect it before it causes harm.
The most-studied marker of systemic inflammation. Elevated hs-CRP roughly doubles cardiovascular risk independent of cholesterol.
An amino acid that, when elevated, damages blood vessels and raises stroke and dementia risk. Usually responds well to B-vitamins.
An older, broader marker of inflammation. Useful in combination with hs-CRP.
A clotting protein elevated in chronic inflammation. High fibrinogen raises stroke and heart attack risk.
Iron storage — but also an acute-phase reactant. Elevated ferritin with normal iron suggests inflammation.
A pro-inflammatory cytokine elevated in chronic inflammation, cardiovascular disease and aging.
A cytokine that drives autoimmune and inflammatory disease.
An enzyme released by white blood cells that destabilises arterial plaque. Predicts cardiovascular events.
A marker of fibrosis and chronic inflammation. Especially predictive of heart failure risk.
Nutrient deficiencies are surprisingly common, even among people who eat well. We measure the vitamins, minerals and fats that have the strongest evidence linking them to health outcomes.
Forty percent of adults are deficient. Links to immunity, mood, bone, hormones and cardiovascular risk. Easy to fix.
Essential for energy, brain health and red blood cell production. Subtle deficiency is common, especially over age 50.
Works with B12 in methylation. Critical for DNA repair and cardiovascular health.
A complete look at iron status. Both deficiency and overload have major consequences.
Iron storage. The most sensitive marker of iron deficiency.
Involved in 300+ enzymatic reactions. RBC magnesium is more accurate than serum.
Critical for immunity, hormones and wound healing. Easily depleted by stress and infection.
Best measured alongside zinc — the ratio matters more than either alone.
A cofactor for antioxidant enzymes and thyroid metabolism.
Essential for thyroid hormone production. Deficiency is rising as iodised salt use falls.
The percentage of EPA + DHA in your red blood cell membranes. One of the strongest predictors of cardiovascular mortality.
High ratios drive inflammation. Western diets are typically 15:1 — optimal is closer to 4:1.
Critical for vision, immunity and reproductive health.
The body's main fat-soluble antioxidant.
Required for bone mineralisation and proper calcium handling.
Powers mitochondria. Declines with age and statin use.
Your liver processes everything you eat, drink and absorb; your kidneys filter your blood every 30 minutes. Together they're the body's most under-appreciated organs. We measure twelve markers to make sure both are doing their job.
A liver enzyme released when liver cells are damaged. Slightly elevated ALT often signals fatty liver.
Another liver enzyme. Higher AST than ALT can indicate alcohol-related liver stress.
A very sensitive marker of liver stress, especially from alcohol or environmental toxins.
An enzyme from liver and bone. Elevated levels can indicate biliary or bone disease.
A breakdown product of red blood cells. Elevated bilirubin indicates liver or biliary issues.
The most abundant protein in blood. Low albumin can indicate liver disease, malnutrition or inflammation.
An estimate of how well your kidneys are filtering. The single most important kidney function marker.
A more precise kidney function marker than creatinine, especially in athletic individuals.
A muscle breakdown product filtered by the kidneys. Used to estimate filtration rate.
A breakdown product of protein. Reflects hydration and kidney function.
High levels cause gout and are strongly linked to metabolic disease and hypertension.
Small amounts of protein in urine — the earliest sign of kidney damage from diabetes or hypertension.
A picture of your red cells, white cells and platelets — the foundations of energy delivery, immunity and clotting. Patterns in the differential can flag everything from anaemia to chronic infection.
The oxygen-carrying protein in red cells. Low haemoglobin causes fatigue and breathlessness.
The percentage of your blood that's red cells. Affected by hydration, altitude and disease.
The number of red cells in a microlitre of blood.
The average size of your red cells. Differentiates types of anaemia.
Red cell distribution width — variation in cell size. Elevated RDW predicts all-cause mortality.
Total immune cells. Elevated levels can indicate infection or chronic inflammation.
Front-line immune cells. Elevated in bacterial infection and inflammation.
Adaptive immune cells, important in viral infection and chronic stress.
Immune cells linked to allergy and parasitic infection.
Critical for clotting. Both high and low platelet counts have clinical meaning.
A simple ratio that's emerged as a powerful general marker of chronic inflammation and aging.
These are the markers used in the world's leading longevity research. They quantify how your body is aging at the molecular level — and which interventions actually move the needle.
An estimate of your cellular age based on DNA methylation patterns. The single most cited marker in longevity research.
Insulin-like growth factor 1 — reflects growth hormone activity. Both too high and too low are problematic.
A protein whose levels predict longevity. Higher klotho is associated with better aging.
A central coenzyme in mitochondrial function. Declines with age in nearly everyone.
The protective caps on your chromosomes. Shorter telomeres correlate with shorter lifespan.
A measure of biological age based on the glycans (sugars) on your antibodies. Responsive to lifestyle changes.
A composite signal of mitochondrial function across several substrates.
A stress signal that rises with mitochondrial dysfunction and aging.
Damaged proteins from chronic high blood sugar. Drive most age-related diseases.
The body's master antioxidant. Higher levels protect against oxidative damage.
Derived from blood markers and biometrics. One of the strongest predictors of all-cause mortality.
These tumor markers are not diagnostic on their own — they are screening signals, useful for trend monitoring and risk stratification when interpreted by a clinician. Included in the Apex panel only.
A screening marker for prostate health (males).
A screening marker for ovarian health (females).
A marker primarily for pancreatic and biliary tract monitoring.
A broad oncology marker, often used for colorectal monitoring.
Used in screening for hepatocellular and testicular cancers.
A marker used in monitoring blood cancers.
Increases the specificity of PSA when elevated.
A general tissue damage marker; useful in monitoring some cancers.
Heavy metals and environmental toxins accumulate slowly and silently. We screen for the most common contaminants and the genetic variants that affect how well your body clears them.
Accumulates from large fish and dental amalgams. Neurotoxic at elevated levels.
No safe level. Old plumbing and certain spices are common sources.
Found in some groundwater, rice and seafood. Long-term exposure raises cancer risk.
From smoking, certain foods and industrial exposure. Accumulates in the kidneys.
From cookware, antiperspirants and water. Excess may contribute to neurodegeneration.
"Forever chemicals" found in water and food packaging. Linked to immune and metabolic dysfunction.
Two of the most well-studied genetic variants. Help personalise your B-vitamin and lipid recommendations.